Cerebral palsy

Cerebral palsy (CP) describes a group of disorders of the development of movement and posture that causes activity limitation. The motor disorders of CP are often accompanied by disturbances of sensation, cognition, communication, perception, and/or behavior and/or by a seizure disorder. The motor disorders include reduced muscle strength and abnormal submaximal motor control, which reduces functional performance and limits physical activity.

The CP research focus in PMR-C is to investigate the effectiveness of physical rehabilitation modalities to improve muscle control, and increase muscle strength, functional performance, and physical activity in CP. We systematically quantify deficits in muscle control, muscle strength, and functional performance – along with other key clinical symptoms – to gain a detailed understanding of these impairments. We then explore the feasibility of impairment-directed physical rehabilitation modalities. The rehabilitation modalities are very simple, they are designed on the basis of identified deficits, and they use a basic exercise physiology rationale. If a rehabilitation modality seems feasible: that is, can be performed progressively with sufficient compliance, the effectiveness of the rehabilitation modality is finally investigated in a randomized controlled design.

PMR-C research within CP is conducted in close collaboration with the Gait Analysis Laboratory, Department of Orthopedic Surgery, Hvidovre Hospital.

Selected papers

Bandholm T, Jensen BR, Nielsen LM, Rasmussen H, Bencke J, Curtis D, Pedersen SA, Sonne-Holm S (2012). Neurorehabilitation with versus without resistance training after botulinum toxin treatment in children with cerebral palsy: a randomized pilot study. NeuroRehabilitation 30: 277-286.

Bandholm, T, Rose MH, Sløk R, Sonne-Holm S, Jensen BR (2009). Ankle torque steadiness is related to muscle activation variability and coactivation in children with cerebral palsy. Muscle Nerve 40: 402-410.

Curtis DJ, Butler P, Saavedra S, Bencke J, Kallemose T, Sonne-Holm S, Woollacott M (2014). The central role of trunk control in the gross motor function of children with cerebral palsy: a retrospective cross-sectional study. Dev Med.Child Neurol (Epub ahead of print). 

Ongoing research
The effect of targeted training on function, seated postural control and daily-life activities in children with cerebral palsy 

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