Neurology

Neurological disorders are associated with a variety of symptoms, including reduced muscle strength, abnormal muscle control, and reduced functional performance. The neurology research focus in PMR-C is to investigate the effectiveness of physical rehabilitation modalities to improve muscle control, and increase muscle strength and functional performance in various neurological disorders. We systematically quantify deficits in muscle control, muscle strength, and functional performance – along with other key clinical symptoms – to gain a detailed understanding of these impairments. We then explore the feasibility of impairment-directed physical rehabilitation modalities. The rehabilitation modalities are very simple, they are designed on the basis of identified deficits, and they use a basic exercise physiology rationale. If a rehabilitation modality seems feasible: that is, can it be performed progressively with sufficient compliance, the effectiveness of the rehabilitation modality is finally investigated in a randomized controlled design.  

Selected papers
Bandholm T, Jensen BR, Nielsen LM, Rasmussen H, Bencke J, Curtis D, Pedersen SA, Sonne-Holm S (2012). Neurorehabilitation with versus without resistance training after botulinum toxin treatment in children with cerebral palsy: a randomized pilot study. NeuroRehabilitation 30: 277-286.

Bandholm, T, Rose MH, Sløk R, Sonne-Holm S, Jensen BR (2009). Ankle torque steadiness is related to muscle activation variability and coactivation in children with cerebral palsy. Muscle Nerve 40: 402-410.

Nielsen JB, Crone C, Hultborn H (2007). The spinal pathophysiology of spasticity – from a basic science point of view. Acta Physiol (Oxf) 189: 171-180.

 


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